A Model for Antagonistic Pleiotropic Gene Action for Mortality and Advanced Age
نویسندگان
چکیده
منابع مشابه
A model for antagonistic pleiotropic gene action for mortality and advanced age.
Association or linkage studies involving control and long-lived populations provide information on genes that influence longevity. However, the relationship between allele-specific differences in survival and the genetic structure of aging cohorts remains unclear. We model a heterogeneous cohort comprising several genotypes differing in age-specific mortality. In its most general form, without ...
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ژورنال
عنوان ژورنال: The American Journal of Human Genetics
سال: 1998
ISSN: 0002-9297
DOI: 10.1086/301865